Untying the Gordian Knot: The Development of an Immunization Information Exchange

Genetics of lupus-untying the Gordian knot!

Untying the Climate - Development Gordian Knot : Economic Options in a Politically Constrained World

Climate policies must deal with a contradiction generic to global environment policies: as was recognized as early as in 1972 at the UN conference on Human Environment at Stockholm, the participation of developing countries is essential. The current emissions of developing countries are also significant. If the trend continues, the future share of global emissions from developing countries will...

Gordian Distance and Vassiliev Invariants

The Gordian distance between two knots measures how many crossing changes are needed to transform one knot into the other. It is known that there are always infinitely many nonequivalent knots ‘between’ a pair of knots of Gordian distance two. In this paper we prove an extreme generalisation of this fact: there are knots with arbitrarily prescribed Vassiliev invariants between every pair of kno...

Untying the Gordian knot: policies, practices, and ethical issues related to banking of umbilical cord blood.

Since the first successful transplantation of umbilical cord blood in 1988, cord blood has become an important source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Significant progress has been accompanied by challenges for scientists, ethicists, and health policy makers. With the recent recognition of the need for a national system for the collect...

Untying knots in proteins.

A shoelace can be readily untied by pulling its ends rather than its loops. Attempting to untie a native knot in a protein can also succeed or fail depending on where one pulls. However, thermal fluctuations induced by the surrounding water affect conformations stochastically and may add to the uncertainty of the outcome. When the protein is pulled by the termini, the knot can only get tightene...